Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843196 | 0.95 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL239123 | 0.95 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL291925 | 0.94 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL241794 | 0.90 | ADORA2A (0.60) | ADORA2AADORA3ADORA1 | |
| SCHEMBL293561 | 0.90 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL293560 | 0.90 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL241166 | 0.90 | ADORA2A (0.55) | ADORA2AADORA3ADORA1 | |
| SCHEMBL243234 | 0.89 | ADORA2A (0.64) | ADORA2AADORA3ADORA1 | |
| SCHEMBL2992497 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3ADORA1 | |
| SCHEMBL2992504 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |