Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408382 | 0.82 | HPGD (1.00) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL6245001 | 0.82 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL14036971 | 0.80 | HPGD (0.65) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL16197468 | 0.80 | HPGD (0.65) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL46426 | 0.79 | NPC1 (1.00) | HPGDNPC1RAB9ASMN1; SMN2NOTUM | |
| SCHEMBL16157140 | 0.78 | SMN1; SMN2 (0.64) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL11120052 | 0.77 | EGFR (0.68) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL9062992 | 0.77 | EGFR (0.68) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL8348993 | 0.77 | CYP1A2 (0.73) | HPGDNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL28786922 | 0.77 | HPGD (0.61) | HPGDNPC1RAB9ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773389-B | Oxadiazole heterocycle substituted quaternary phosphonium salt with antibacterial activity, and preparation method and application thereof | 中国医学科学院整形外科医院 | 2023-08-29 | — | — | CN | disclosed |
| CN-114773389-A | Oxadiazole heterocycle substituted quaternary phosphonium salt with bacteriostatic activity and preparation method and application thereof | 中国医学科学院整形外科医院 | 2022-07-22 | — | — | CN | disclosed |