SCHEMBL46426

SCHEMBL46426

c1ccc(-c2nnc(-c3ccccc3)o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 13/20 1.00
RAB9A P51151 13/20 1.00
SMN1; SMN2 Q16637 8/20 1.00
ATAD2 Q6PL18 1/20 0.77
HPGD P15428 6/20 0.74
NFKB1 P19838 2/20 0.74
NFKB2 Q00653 2/20 0.74
RELA Q04206 2/20 0.74
POLB P06746 2/20 0.74
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
ALDH1A1 P00352 5/20 0.71
KDM4E B2RXH2 3/20 0.71
HSD17B10 Q99714 2/20 0.71
GLA P06280 1/20 0.71
MAPT P10636 1/20 0.71
ALOX15 P16050 1/20 0.71
NOTUM Q6P988 4/20 0.70
TSHR P16473 4/20 0.65
TP53 P04637 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4343181 0.97 NPC1 (0.94) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL74999 0.95 NPC1 (0.90) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL522555 0.95 NPC1 (0.90) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL46424 0.95 NPC1 (0.90) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL22858502 0.95 NPC1 (0.90) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL12765577 0.92 NPC1 (0.85) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL1105099 0.92 NPC1 (0.85) NPC1RAB9ASMN1; SMN2ATAD2HPGD
Dimethylamine SCHEMBL9350461 0.90 RAB9A (0.81) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL14378791 0.90 NPC1 (0.81) NPC1RAB9ASMN1; SMN2ATAD2HPGD
SCHEMBL17614675 0.90 NPC1 (0.81) NPC1RAB9ASMN1; SMN2ATAD2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798658-A Slurry, preparation method and application thereof, and high-thermal-conductivity polyimide film 济南新材料产业技术研究院 2025-04-11 CN claimed
CN-114671969-B Polystyrene scintillating particles and preparation method thereof 中国辐射防护研究院 2024-04-12 CN claimed
CN-114685704-A Plastic scintillation microsphere and synthetic method thereof 中国辐射防护研究院 2022-07-01 CN claimed
CN-114671969-A Polystyrene scintillation particle and preparation method thereof 中国辐射防护研究院 2022-06-28 CN claimed
CN-114672103-A Plastic scintillation microsphere and preparation method thereof 中国辐射防护研究院 2022-06-28 CN claimed
CN-113185628-A Polystyrene scintillation microsphere and preparation method thereof 中国辐射防护研究院 2021-07-30 CN claimed
US-10732304-B1 Hydrothermal aging-resistant plastic scintillator formulations NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2020-08-04 US claimed
CN-109553878-A A kind of preparation method of low temperature resistant polyvinyl chloride cable material 王龙波 2019-04-02 CN claimed
CN-109553879-A A kind of low temperature resistant polyvinyl chloride cable material 王龙波 2019-04-02 CN claimed
CN-109553880-A A kind of polyvinyl chloride cable material 王龙波 2019-04-02 CN claimed
EP-0606198-A1 MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) THE DOW CHEMICAL COMPANY (US) 1994-07-20 EP claimed
US-5246647-A Solvent THE DOW CHEMICAL COMPANY (US) 1993-09-21 US claimed
US-5227101-A Blending, heating, extruding or casting, quenching or coagulating and leaching a blend of unsulfonated polyether ketone copolymers and partially imcompatible polymer THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
US-5205968-A Process for making a microporous membrane from a blend containing a poly(etheretherketone)-type polymer, an amorphous polymer, and a solvent THE DOW CHEMICAL COMPANY (US) 1993-04-27 US claimed
WO-1993004223-A1 MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) THE DOW CHEMICAL COMPANY (US) 1993-03-04 WO claimed
US-5064580-A Heating, extrusion, coagulation, leaching out of plasticizer THE DOW CHEMICAL COMPANY (US) 1991-11-12 US claimed
US-5057600-A Dissolving in organic compound, shaping THE DOW CHEMICAL COMPANY (US) 1991-10-15 US claimed
US-5043112-A Dissolving polyphenylene sulfide in hot melted high-boiling boiling organic solvent, shaping, desolventizing, cooling THE DOW CHEMICAL COMPANY (US) 1991-08-27 US claimed
US-4904426-A MOCROPOROUS; AROMATIC RING-CONTAINING SOLVENT; EXTRUSION, QUENCHING, LEACHING, DRYING THE DOW CHEMICAL COMPANY (US) 1990-02-27 US claimed
US-4897307-A FILM, MEMBRANE, SHEET, FIBER THE DOW CHEMICAL COMPANY (US) 1990-01-30 US claimed