Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516167 | 0.85 | EPHX2 (1.00) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27735879 | 0.83 | EPHX2 (0.96) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5447986 | 0.82 | FFAR1 (0.84) | RAB9ASMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL9478851 | 0.82 | EPHX2 (0.85) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4420812 | 0.82 | EPHX2 (0.79) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13290702 | 0.82 | EPHX2 (0.79) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5175200 | 0.82 | EPHX2 (0.79) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10054999 | 0.81 | EPHX2 (0.92) | EPHX2PRMT1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18601428 | 0.81 | KMT2A (0.68) | EPHX2PRMT1RAB9AALDH1A1MAPT | |
| SCHEMBL18415584 | 0.81 | PTPN1 (0.71) | RAB9AALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084710-A | Kv7 potassium ion channel opener, and pharmaceutical composition and application thereof | 青岛海枢康制药有限公司 | 2024-05-28 | — | — | CN | disclosed |