Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744942 | 0.86 | HDAC6 (0.68) | EPHX2HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL675578 | 0.84 | KMT2A (0.76) | KMT2AMEN1EPHX2HDAC2HDAC8 | |
| SCHEMBL22664681 | 0.84 | HDAC1 (0.69) | KMT2AMEN1HDAC2HDAC8HDAC6 | |
| SCHEMBL11900090 | 0.83 | HDAC6 (0.85) | EPHX2HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL14811272 | 0.83 | HDAC6 (0.78) | KMT2AMEN1EPHX2HDAC2HDAC8 | |
| SCHEMBL22196106 | 0.83 | KMT2A (0.78) | KMT2AMEN1EPHX2HDAC2HDAC8 | |
| SCHEMBL18275331 | 0.83 | RORC (0.57) | KMT2AMEN1HDAC3POLBKDM4E | |
| SCHEMBL7097847 | 0.82 | EPHX2 (0.76) | KMT2AMEN1EPHX2HDAC2HDAC8 | |
| SCHEMBL22664696 | 0.81 | MEN1 (0.74) | KMT2AMEN1HDAC2HDAC8HDAC6 | |
| SCHEMBL29246754 | 0.81 | EPHX2 (0.73) | KMT2AMEN1EPHX2HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2713722-B1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | RECEPTOS LLC (US) | 2017-03-15 | — | — | EP | disclosed |