Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232600 | 0.90 | OPRD1 (0.44) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL5225612 | 0.87 | OPRD1 (0.42) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL28607334 | 0.82 | OPRD1 (0.43) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL1049597 | 0.81 | OPRD1 (0.49) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL5228906 | 0.80 | OPRD1 (0.43) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL19124768 | 0.80 | OPRD1 (0.46) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL5230631 | 0.80 | OPRD1 (0.43) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL6039864 | 0.79 | JAK2 (0.43) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL17467896 | 0.79 | OPRD1 (0.45) | OPRD1OPRK1GPR119JAK2JAK1 | |
| SCHEMBL7056058 | 0.79 | TACR1 (0.42) | OPRD1OPRK1GPR119JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |