Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OGT | O15294 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29247154 | 0.90 | GPR119 (0.41) | TP53LMNATHRB | |
| SCHEMBL30294951 | 0.90 | GPR119 (0.41) | TP53LMNATHRB | |
| SCHEMBL29247404 | 0.90 | GPR119 (0.41) | TP53LMNATHRB | |
| SCHEMBL29247492 | 0.85 | LIMK2 (0.37) | TP53MAPTSMOTSHRCRHBP | |
| SCHEMBL30295267 | 0.81 | GPR119 (0.40) | TSHR | |
| SCHEMBL15401147 | 0.80 | NPC1 (0.40) | TP53MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL29247410 | 0.79 | CNR1 (0.41) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL30372392 | 0.78 | GPR119 (0.41) | KMT2AMEN1 | |
| SCHEMBL29247409 | 0.78 | GPR119 (0.41) | KMT2AMEN1 | |
| SCHEMBL29247058 | 0.78 | SMO (0.42) | MAPTSMOTSHRKMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |