Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29248071 | 1.00 | FBP1 (0.65) | FBP1TRPA1MAOBMAOAALDH1A1 | |
| SCHEMBL29248025 | 0.82 | FBP1 (0.65) | FBP1MAOBMAOAALDH1A1PTGS2 | |
| SCHEMBL29248020 | 0.82 | FBP1 (0.65) | FBP1MAOBMAOAALDH1A1PTGS2 | |
| SCHEMBL29247991 | 0.81 | FBP1 (0.48) | FBP1MAOBMAOAALDH1A1PTGS2 | |
| SCHEMBL29247989 | 0.81 | FBP1 (0.48) | FBP1MAOBMAOAALDH1A1PTGS2 | |
| SCHEMBL29248047 | 0.81 | FBP1 (0.49) | FBP1ALDH1A1MAPT | |
| SCHEMBL29248045 | 0.81 | FBP1 (0.49) | FBP1ALDH1A1MAPT | |
| SCHEMBL21631226 | 0.80 | FBP1 (0.60) | FBP1ALDH1A1 | |
| SCHEMBL21631225 | 0.80 | FBP1 (0.60) | FBP1ALDH1A1 | |
| SCHEMBL29248015 | 0.78 | FBP1 (0.54) | FBP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655536-A | Class N 1 -aryl-3-fluoroalkyl-5-fluoropyrazole compound, and preparation method and application thereof | 天津大学 | 2023-08-29 | — | — | CN | disclosed |