Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429790 | 0.81 | CYP3A4 (0.34) | TSHR | |
| SCHEMBL3816214 | 0.77 | TSHR (0.60) | TSHR | |
| SCHEMBL1486113 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL17999714 | 0.75 | CYP2C19 (0.33) | TSHR | |
| SCHEMBL194036 | 0.75 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL6808152 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL6449351 | 0.74 | TSHR (0.44) | TSHR | |
| SCHEMBL486485 | 0.74 | TSHR (0.31) | TSHR | |
| SCHEMBL16072566 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL3815405 | 0.73 | CYP3A4 (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027098-A | Prodrugs of ospirimol and derivatives thereof, and preparation method and application thereof | 珠海安哲医药科技有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118027098-A | Prodrugs of ospirimol and derivatives thereof, and preparation method and application thereof | 珠海安哲医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116874531-A | New preparation method of antiemetic medicine | 北京康立生医药技术开发有限公司 | 2023-10-13 | — | — | CN | disclosed |