Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.45 |
| ▸ | VEGFA | P15692 | 5/20 | 0.45 |
| ▸ | FLT1 | P17948 | 5/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257616 | 0.91 | SMN1; SMN2 (0.41) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL29248907 | 0.81 | ESR2 (0.33) | — | |
| SCHEMBL1920951 | 0.79 | EGLN1 (0.56) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257741 | 0.78 | SMN1; SMN2 (0.39) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257815 | 0.78 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL30452393 | 0.78 | SMN1; SMN2 (0.38) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL24257751 | 0.76 | EGLN1 (0.50) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL29248923 | 0.76 | DPP4 (0.36) | — | |
| SCHEMBL26260293 | 0.75 | EGLN1 (0.52) | EGLN1VEGFAFLT1EGLN3 | |
| SCHEMBL30452382 | 0.75 | SMN1; SMN2 (0.37) | EGLN1VEGFAFLT1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670131-A | PHD inhibitor compounds, compositions, and methods of use | 阿克比治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |