SCHEMBL29249162

SCHEMBL29249162

CCCCCCCC/C=C\CCCCCCCCS(=O)(=O)OC.[NaH]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.56
TRPV1 Q8NER1 2/20 0.48
EPHX2 P34913 2/20 0.47
PPARA Q07869 3/20 0.46
ALDH1A1 P00352 2/20 0.43
DUSP3 P51452 1/20 0.43
PTPN7 P35236 1/20 0.43
KDM4E B2RXH2 1/20 0.43
FFAR1 O14842 1/20 0.43
LMNA P02545 1/20 0.43
FABP3 P05413 1/20 0.43
CYP3A4 P08684 1/20 0.43
F7 P08709 1/20 0.43
CYP19A1 P11511 1/20 0.43
F3 P13726 1/20 0.43
FABP4 P15090 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284906 0.88 FAAH (0.50) FAAHEPHX2HPGDTSHR
SCHEMBL25250335 0.88 FAAH (0.50) FAAHEPHX2HPGDTSHR
SCHEMBL27780504 0.88 FAAH (0.50) FAAHEPHX2HPGDTSHR
SCHEMBL27839691 0.88 FAAH (0.50) FAAHEPHX2HPGDTSHR
SCHEMBL10780945 0.86 FAAH (0.52) FAAHEPHX2HPGDTSHR
SCHEMBL7142815 0.86 FAAH (0.52) FAAHEPHX2HPGDTSHR
SCHEMBL2384630 0.86 FAAH (0.52) FAAHEPHX2HPGDTSHR
SCHEMBL20543431 0.86 FAAH (0.46) FAAH
SCHEMBL11236132 0.86 FAAH (0.52) FAAHEPHX2HPGDTSHR
SCHEMBL11414419 0.86 FAAH (0.52) FAAHEPHX2HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118175993-A Anti-SOST antibody pharmaceutical composition and application thereof 江苏恒瑞医药股份有限公司 2024-06-11 CN disclosed