SCHEMBL29249166

SCHEMBL29249166

CN(C)c1ccc(-c2ccc(P(C3CCCCC3)C3CCCCC3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.38
EPHX1 P07099 1/20 0.38
HRH3 Q9Y5N1 3/20 0.38
HRH4 Q9H3N8 1/20 0.38
GAA P10253 2/20 0.37
HPGD P15428 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ROCK2 O75116 1/20 0.37
ALOX5 P09917 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
ADK P55263 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
NOX4 Q9NPH5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14742456 0.95 ALDH1A1 (0.42) ALDH1A1KDM4ETSHRHSD17B10ALOX15
SCHEMBL16965449 0.93 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRHSD17B10ALOX15
SCHEMBL16965741 0.93 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRHSD17B10ALOX15
SCHEMBL20994189 0.93 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1KDM4ETSHRHSD17B10
Hydrochloric Acid SCHEMBL9938484 0.91 ALDH1A1 (0.40) ALDH1A1KDM4ETSHRHSD17B10ALOX15
Hydrochloric Acid SCHEMBL9938486 0.91 ALDH1A1 (0.40) MAPTSMN1; SMN2ALDH1A1KDM4ETSHR
SCHEMBL1701442 0.88 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRHSD17B10ALOX15
Formaldehyde SCHEMBL16965859 0.88 EPHX1 (0.40) SMN1; SMN2ALDH1A1KDM4ETSHRHSD17B10
SCHEMBL30594614 0.88 ALDH1A1 (0.41) ALDH1A1KDM4ETSHRHSD17B10ALOX15
Formaldehyde SCHEMBL16965494 0.88 EPHX1 (0.40) SMN1; SMN2ALDH1A1KDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043308-A Bond formation method based on coupling reaction 中外制药株式会社 2024-05-14 CN disclosed