Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 12/20 | 0.61 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.61 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249424 | 0.88 | MTOR (0.61) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249433 | 0.88 | ALDH1A1 (0.57) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249426 | 0.88 | MTOR (0.62) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL23839859 | 0.86 | MTOR (0.64) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249566 | 0.85 | MTOR (0.64) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249407 | 0.83 | KMT2A (0.43) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249434 | 0.82 | MTOR (0.47) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249438 | 0.82 | MTOR (0.43) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249413 | 0.81 | MTOR (0.65) | MTORRPTORMLST8ALDH1A1KMT2A | |
| SCHEMBL29249408 | 0.81 | MTOR (0.63) | MTORRPTORMLST8ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368279-B | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2024-05-28 | — | — | CN | claimed |
| CN-112368279-B | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2024-05-28 | — | — | CN | disclosed |