Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28744834 | 0.82 | POLB (0.45) | POLBCASP6PIN1MEN1KMT2A | |
| SCHEMBL29250581 | 0.78 | MAPK1 (0.54) | KDR | |
| SCHEMBL24392929 | 0.78 | PIN1 (0.43) | ALDH1A1GAAPOLBCASP6PIN1 | |
| SCHEMBL30584579 | 0.78 | PIN1 (0.43) | ALDH1A1GAAPOLBCASP6PIN1 | |
| SCHEMBL30584582 | 0.73 | PIN1 (0.56) | ALDH1A1GAAPIN1MEN1KMT2A | |
| SCHEMBL29250669 | 0.73 | PIN1 (0.56) | ALDH1A1GAAPIN1MEN1KMT2A | |
| SCHEMBL29537662 | 0.73 | BTK (0.53) | EGFR | |
| SCHEMBL24392927 | 0.73 | BTK (0.53) | EGFR | |
| SCHEMBL24393178 | 0.72 | SYK (0.43) | ALDH1A1METKDRMEN1KMT2A | |
| SCHEMBL28744862 | 0.72 | POLB (0.43) | POLBCASP6PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |