SCHEMBL2925236

SCHEMBL2925236

O=C(O)CCOc1cccc2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
ALDH1A1 P00352 3/20 0.70
HPGD P15428 3/20 0.70
TDP1 Q9NUW8 1/20 0.70
KCNA3 P22001 1/20 0.60
LMNA P02545 1/20 0.60
HTR1B P28222 6/20 0.59
MCL1 Q07820 3/20 0.59
CNR2 P34972 1/20 0.58
ATM Q13315 1/20 0.55
HTR1D P28221 2/20 0.54
OGG1 O15527 1/20 0.54
SLC6A4 P31645 1/20 0.53
HRH1 P35367 1/20 0.53
MRGPRX4 Q96LA9 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29865765 1.00 KDM4E (0.70) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL29865493 0.92 KDM4E (0.68) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL5488944 0.92 KDM4E (0.68) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL20911356 0.90 CNR2 (0.71) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL29865967 0.90 CNR2 (0.71) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL8357769 0.89 CNR2 (0.69) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL20886144 0.89 CNR2 (0.69) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL4294120 0.89 CNR2 (0.69) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL29865585 0.89 CNR2 (0.69) KDM4EALDH1A1HPGDTDP1KCNA3
SCHEMBL29865545 0.89 CNR2 (0.69) KDM4EALDH1A1HPGDTDP1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4766220-A REACTING OPTICALLY ACTIVE ALKALI METAL SALTS OF 2-HALOGENOALKANOIC ACIDS AND PHENOLS IN WATER WITH HEATING AT REDUCED PRESSURE RHONE-POULENC AGROCHIMIE (FR) 1988-08-23 US claimed
JP-62201572-A None JP disclosed
JP-54076823-A None JP disclosed
JP-62010041-A None JP disclosed
US-20190106592-A1 HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS BASF COATINGS GMBH (DE) 2019-04-11 US disclosed
EP-2146574-B1 PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N, N-DIETHYL-2-( - NAPHTHOXY) PROPIONAMIDE UPL LTD (IN) 2015-11-04 EP disclosed
EP-2146574-A2 PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N, N-DIETHYL-2-( - NAPHTHOXY) PROPIONAMIDE United Phosphorus Limited (IN) 2010-01-27 EP disclosed
WO-2009004642-A2 PROCESS FOR MANUFACTURE OF HIGH PURITY D-(-)-N, N-DIETHYL-2-(α- NAPHTHOXY) PROPIONAMIDE UNITED PHOSPHORUS LIMITED (IN) 2009-01-08 WO disclosed
US-20080107829-A1 Cellulose compound, cellulose film, optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-05-08 US disclosed
US-7157430-B2 (Substituted)acyl dipeptidyl inhibitors of the ICE/CED-3 family of cysteine proteases IDUN PHARMACEUTICALS, INC. (US) 2007-01-02 US disclosed
US-6242422-B1 (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases IDUN PHARMACUETICALS, INC. 2001-06-05 US disclosed
WO-2000023421-A1 (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES IDUN PHARMACEUTICALS, INC. (US) 2000-04-27 WO disclosed
US-4766220-A REACTING OPTICALLY ACTIVE ALKALI METAL SALTS OF 2-HALOGENOALKANOIC ACIDS AND PHENOLS IN WATER WITH HEATING AT REDUCED PRESSURE RHONE-POULENC AGROCHIMIE (FR) 1988-08-23 US disclosed
EP-0122426-B1 OPTICALLY ACTIVE CHROMAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES BASF Aktiengesellschaft (DE) 1988-01-27 EP disclosed
JP-S62201572-A INDUCING MEDIUM FOR CALLUS MITSUI TOATSU CHEM INC 1987-09-05 JP disclosed
US-4645845-A Novel optically active chroman derivatives, their preparation and novel intermediates BASF AKTIENGESELLSCHAFT (DE) 1987-02-24 US disclosed
JP-S6210041-A NAPHTHOXYPROPIONIC ACID DERIVATIVE, PRODUCTION THEREOF AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT SUMITOMO CHEM CO LTD 1987-01-19 JP disclosed
EP-0122426-A2 Optically active chroman derivatives, process for their preparation and intermediates BASF Aktiengesellschaft (DE) 1984-10-24 EP disclosed
JP-S5476823-A HERBICIDAL COMPOSITION FOR PADDY RICE FIELD. MITSUI TOATSU CHEM INC 1979-06-19 JP disclosed
JP-S05476823-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190106592-A1 HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS TYR, PAH, AHR KDM4E 3003/4885ALDH1A1 224/4885HPGD 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.