Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.61 |
| ▸ | HTR1B | P28222 | 4/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 3/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.54 |
| ▸ | BAD | Q92934 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865493 | 1.00 | KDM4E (0.68) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL29865967 | 0.95 | CNR2 (0.71) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL20911356 | 0.95 | CNR2 (0.71) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL20898049 | 0.94 | KCNA3 (0.74) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL20886144 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL4294120 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL29865585 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL8357769 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL29865545 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 | |
| SCHEMBL8780102 | 0.94 | CNR2 (0.69) | KDM4EALDH1A1HPGDTDP1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066774-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |
| WO-2019072553-A1 | HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS | BASF COATINGS GMBH (DE) | 2019-04-18 | — | — | WO | disclosed |
| US-20190106592-A1 | HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS | BASF COATINGS GMBH (DE) | 2019-04-11 | — | — | US | disclosed |
| US-7157430-B2 | (Substituted)acyl dipeptidyl inhibitors of the ICE/CED-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20040259804-A1 | (Substituted)Acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. | 2004-12-23 | — | — | US | disclosed |
| US-20020091089-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | KARANEWSKY DONALD S (US) | 2002-07-11 | — | — | US | disclosed |
| EP-1123272-A1 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals, Inc. (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6242422-B1 | (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases | IDUN PHARMACUETICALS, INC. | 2001-06-05 | — | — | US | disclosed |
| WO-2000023421-A1 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0662964-B1 | HETEROCYCLIC AMINES HAVING CALMODULIN ANTAGONIST PROPERTIES | BRITISH TECH GROUP (GB) | 1997-06-11 | — | — | EP | disclosed |
| US-5543422-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS, FUNGICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-08-06 | — | — | US | disclosed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
| US-5278148-A | Hypotensive agents | HOFFMANN-LA ROCHE INC. (US) | 1994-01-11 | — | — | US | disclosed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-5140011-A | Hypotensive agents | HOFFMANN-LA ROCHE, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106592-A1 | HYPERBRANCHED POLYMERS FOR ORGANIC PIGMENT DISPERSIONS AND WATER-SENSITIVE PIGMENTS | TYR, PAH, AHR | KDM4E 3003/4885ALDH1A1 224/4885HPGD 346/4885 |
| US-20020091089-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | KDM4E 2593/4885ALDH1A1 2658/4885HPGD 4182/4885 |
| US-20040259804-A1 | (Substituted)Acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | KDM4E 2593/4885ALDH1A1 2658/4885HPGD 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.