Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29253233 | 0.92 | ACE2 (0.42) | ACE2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL29282257 | 0.90 | HDAC1 (0.45) | ACE2GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL29152598 | 0.89 | ACE2 (0.47) | ACE2GRIK1GRIK2CA2MAPK1 | |
| SCHEMBL28664768 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL7367485 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL28381502 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL18597120 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL18597124 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL22880855 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL28380817 | 0.86 | CA2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201916-A | Piperazinylsulfonylaryl compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-06-14 | — | — | CN | disclosed |