Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31196227 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL7907171 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL18627981 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL31370678 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL1297228 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL18740467 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL7907151 | 0.92 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL1169394 | 0.92 | MAPT (0.52) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| Ethylene Glycol SCHEMBL1296443 | 0.88 | ALDH1A1 (0.45) | PPM1BPTPN1PPP1CCMAPTALDH1A1 | |
| SCHEMBL1297532 | 0.88 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388409-A | HDAC6/JNK3 double-target anti-Alzheimer disease inhibitor and preparation method and application thereof | 山东大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-118108734-A | Sesquiterpene lactone derivative and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |