SCHEMBL2925447

SCHEMBL2925447

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)OOC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.35
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8717900 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL22653573 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL6685847 0.96 LMNA (0.37) LMNATHRB
SCHEMBL7755900 0.87 LMNA (0.32) LMNA
SCHEMBL9310693 0.85 LMNA (0.32) LMNA
SCHEMBL29263774 0.82 LMNA (0.35) LMNA
SCHEMBL3629816 0.79 LMNA (0.42) LMNATHRBCA2
SCHEMBL9589771 0.79 LMNA (0.42) LMNATHRBCA2
SCHEMBL3313899 0.79 LMNA (0.42) LMNATHRBCA2
SCHEMBL11511027 0.79 LMNA (0.42) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252398-B2 Adhesive vinylidene fluoride resin sheet KUREHA CORPORATION (JP) 2012-08-28 US disclosed
EP-2226338-B1 ADHESIVE VINYLIDENE FLUORIDE RESIN SHEET KUREHA CORP (JP) 2012-08-15 EP disclosed
US-20100285254-A1 ADHESIVE VINYLIDENE FLUORIDE RESIN SHEET KUREHA CORPORATION (JP) 2010-11-11 US disclosed
EP-2226338-A1 ADHESIVE VINYLIDENE FLUORIDE RESIN SHEET Kureha Corporation (JP) 2010-09-08 EP disclosed
EP-0950672-B1 Method for producing a fluorine-containing polymer ASAHI GLASS CO LTD (JP) 2003-09-17 EP disclosed
US-6221987-B1 BULK POLYMERIZATION ASAHI GLASS COMPANY LTD. (JP) 2001-04-24 US disclosed
EP-0950672-A1 Method for producing a fluorine-containing polymer Asahi Glass Company Ltd. (JP) 1999-10-20 EP disclosed