Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.62 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.62 |
| ▸ | THRA | P10827 | 10/20 | 0.48 |
| ▸ | THRB | P10828 | 10/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925524 | 0.84 | EGLN1 (0.69) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1031799 | 0.79 | EGLN1 (0.69) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522744 | 0.77 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL29390250 | 0.77 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523089 | 0.77 | EGLN1 (0.66) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL5030157 | 0.76 | EGLN1 (0.58) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL29724635 | 0.76 | EGLN1 (0.72) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522017 | 0.76 | EGLN1 (0.72) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522079 | 0.76 | EGLN1 (0.72) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523155 | 0.75 | EGLN1 (0.71) | EGLN1FTOBBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227232-A1 | METHODS FOR INHIBITING T HELPER CELL DIFFERENTIATION | Fibrogen, Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009075822-A1 | METHODS FOR INHIBITING T HELPER CELL DIFFERENTIATION | FIBROGEN, INC. (US) | 2009-06-18 | — | — | WO | disclosed |