Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.69 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.69 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.69 |
| ▸ | THRA | P10827 | 10/20 | 0.55 |
| ▸ | THRB | P10828 | 10/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523089 | 0.84 | EGLN1 (0.66) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL2925524 | 0.84 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522079 | 0.83 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL29724635 | 0.83 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522744 | 0.82 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL29390250 | 0.82 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522017 | 0.81 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523057 | 0.80 | THRB (0.73) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523155 | 0.80 | EGLN1 (0.71) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL2925489 | 0.79 | EGLN1 (0.62) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | claimed |