Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 1/20 | 0.50 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772165 | 0.85 | FFAR1 (0.51) | HSP90AB1HSD17B1SLC7A5FFAR1ESR1 | |
| SCHEMBL5536200 | 0.85 | CYP4F2 (0.50) | HSP90AB1HSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL29255229 | 0.84 | DHODH (0.45) | HSP90AB1HSD17B1HSD17B2SLC7A5FFAR1 | |
| SCHEMBL13791195 | 0.82 | HSP90AB1 (0.54) | HSP90AB1HSD17B1HSD17B2SLC7A5ALDH1A1 | |
| SCHEMBL13433607 | 0.80 | HSP90AB1 (0.53) | SHMT1SHMT2HSP90AB1HSD17B1HSD17B2 | |
| SCHEMBL30435086 | 0.78 | HSP90AB1 (0.67) | HSP90AB1SLC7A5ALDH1A1GAAGFER | |
| SCHEMBL979023 | 0.78 | HSP90AB1 (0.67) | HSP90AB1SLC7A5ALDH1A1GAAGFER | |
| SCHEMBL7035349 | 0.78 | ALDH1A1 (0.50) | HSP90AB1SLC7A5ALDH1A1GAAGFER | |
| SCHEMBL3361035 | 0.77 | SLC7A5 (0.54) | HSP90AB1SLC7A5FFAR1ALDH1A1GAA | |
| SCHEMBL15564511 | 0.76 | AKR1C3 (0.51) | HSP90AB1SLC7A5ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |