SCHEMBL29255200

SCHEMBL29255200

Cc1ccc(S(=O)(=O)OC[C@H](CC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
CYP2D6 P10635 1/20 0.40
CA2 P00918 4/20 0.39
CA1 P00915 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
ABCB1 P08183 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
STAT3 P40763 1/20 0.38
AAK1 Q2M2I8 1/20 0.38
ATM Q13315 1/20 0.37
P2RX7 Q99572 2/20 0.37
MMP13 P45452 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PTPRB P23467 1/20 0.36
NR1D1 P20393 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30096762 0.94 ALDH1A1 (0.41) ALDH1A1TSHRCA2CA1CA4
SCHEMBL30096737 0.94 ALDH1A1 (0.41) ALDH1A1TSHRCA2CA1CA4
SCHEMBL29255314 0.91 ALDH1A1 (0.44) ALDH1A1TSHRCA2CA1CA4
SCHEMBL30271540 0.89 ALDH1A1 (0.41) ALDH1A1TSHRCA2CA1CA4
SCHEMBL12944323 0.89 ALDH1A1 (0.43) ALDH1A1TSHRCA2CA1CA4
SCHEMBL8193095 0.88 ALDH1A1 (0.43) ALDH1A1TSHRCA2CA1CA4
SCHEMBL1764913 0.87 ALDH1A1 (0.42) ALDH1A1TSHRCA2CA1CA4
SCHEMBL1764915 0.87 ALDH1A1 (0.42) ALDH1A1TSHRCA2CA1CA4
SCHEMBL15627953 0.86 AAK1 (0.52) ALDH1A1TSHRCA2CA1CA4
SCHEMBL10506905 0.86 SYK (0.45) ALDH1A1TSHRCA2CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307534-A LTA4H inhibitors and uses thereof 上海海雁医药科技有限公司 2024-07-09 CN disclosed