Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434762 | 0.85 | RAB9A (0.69) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL21972670 | 0.85 | HTT (0.61) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL21905597 | 0.85 | HTT (0.63) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL750897 | 0.84 | POLB (1.00) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL3487973 | 0.84 | POLB (1.00) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL24124213 | 0.83 | POLB (0.76) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL7489627 | 0.82 | POLB (0.63) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL5094084 | 0.81 | HTT (0.58) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL2241634 | 0.80 | POLB (0.52) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL25925110 | 0.78 | RAB9A (0.76) | POLBSMN1; SMN2HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384267-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2024-06-19 | — | — | EP | disclosed |
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |