Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769102 | 1.00 | STING1 (0.50) | STING1MAPTKMT2AMEN1HPGD | |
| SCHEMBL23769104 | 0.91 | STING1 (0.48) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL25138410 | 0.91 | STING1 (0.48) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL23769101 | 0.89 | STING1 (0.49) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL23769096 | 0.89 | STING1 (0.49) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL30128427 | 0.87 | STING1 (0.61) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL21932185 | 0.87 | STING1 (0.61) | STING1MAPTKMT2AMEN1HDAC6 | |
| SCHEMBL23768984 | 0.85 | STING1 (0.45) | STING1MAPTKMT2AMEN1HPGD | |
| SCHEMBL21932216 | 0.82 | STING1 (0.73) | STING1MAPTKMT2AMEN1POLB | |
| SCHEMBL21932350 | 0.82 | STING1 (0.73) | STING1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | disclosed |