Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138410 | 1.00 | STING1 (0.48) | STING1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL23769102 | 0.91 | STING1 (0.50) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL29256261 | 0.91 | STING1 (0.50) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL23769096 | 0.86 | STING1 (0.49) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL23769101 | 0.86 | STING1 (0.49) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL30128427 | 0.84 | STING1 (0.61) | STING1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL21932185 | 0.84 | STING1 (0.61) | STING1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL29256253 | 0.83 | ELANE (0.41) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL29256250 | 0.83 | ELANE (0.41) | STING1HDAC6KMT2AMEN1POLB | |
| SCHEMBL23768984 | 0.83 | STING1 (0.45) | STING1HDAC6KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |