Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015756 | 0.73 | EGFR (0.44) | — | |
| SCHEMBL29509069 | 0.72 | EGFR (0.35) | — | |
| SCHEMBL29015712 | 0.69 | EGFR (0.49) | — | |
| SCHEMBL29015716 | 0.69 | ALK (0.39) | — | |
| SCHEMBL29974928 | 0.67 | EGFR (0.42) | — | |
| SCHEMBL29084071 | 0.67 | EGFR (0.42) | — | |
| SCHEMBL29083957 | 0.67 | EGFR (0.41) | — | |
| SCHEMBL29975295 | 0.67 | EGFR (0.41) | — | |
| SCHEMBL24327368 | 0.66 | EGFR (0.59) | — | |
| SCHEMBL24328401 | 0.65 | EGFR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745280-A | Bifunctional compounds for degrading EGFR and related methods of use | 百济神州有限公司 | 2023-09-12 | — | — | CN | disclosed |