Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.61 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 9/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29257343 | 0.94 | ALK (0.62) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257391 | 0.92 | ALK (0.62) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL27031725 | 0.90 | ALK (0.61) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257362 | 0.89 | ALK (0.61) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257357 | 0.89 | ALK (0.61) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257363 | 0.89 | ALK (0.61) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257368 | 0.89 | ALK (0.53) | ALKEGFRCRBNPTK2 | |
| SCHEMBL25261949 | 0.89 | EGFR (0.65) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL29257341 | 0.88 | ALK (0.57) | ALKEGFRCRBNPTK2INSR | |
| SCHEMBL24351281 | 0.88 | ALK (0.60) | ALKEGFRCRBNPTK2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745280-A | Bifunctional compounds for degrading EGFR and related methods of use | 百济神州有限公司 | 2023-09-12 | — | — | CN | disclosed |