Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.48 |
| ▸ | PLK4 | O00444 | 6/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29257352 | 1.00 | ALK (0.48) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL29257393 | 1.00 | ALK (0.48) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL29257335 | 0.98 | ALK (0.48) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL24351639 | 0.90 | ALK (0.47) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL24351644 | 0.90 | ALK (0.47) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL27133244 | 0.90 | ALK (0.47) | ALKPLK4PTK2CRBNHPGDS | |
| SCHEMBL29257368 | 0.90 | ALK (0.53) | ALKPLK4PTK2CRBNEGFR | |
| SCHEMBL29257363 | 0.89 | ALK (0.61) | ALKPTK2CRBNEGFR | |
| SCHEMBL29257357 | 0.89 | ALK (0.61) | ALKPTK2CRBNEGFR | |
| SCHEMBL29257362 | 0.89 | ALK (0.61) | ALKPTK2CRBNEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745280-A | Bifunctional compounds for degrading EGFR and related methods of use | 百济神州有限公司 | 2023-09-12 | — | — | CN | disclosed |