Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.47 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.44 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | APEX1 | P27695 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354169 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL31544055 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL9136499 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL23607552 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL5079732 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL23607540 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL31544038 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL9130302 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| Hydrochloric Acid SCHEMBL6403357 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 | |
| SCHEMBL27552592 | 1.00 | TSHR (0.65) | TSHRAPEX1POLBHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240135-A | Emulsion polymer for low-permeability heavy oil reservoir pressure flooding and preparation method thereof | 中国石油化工股份有限公司 | 2024-06-25 | — | — | CN | disclosed |