Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.62 |
| ▸ | ITGAV | P06756 | 20/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.62 |
| ▸ | ITGB5 | P18084 | 11/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344741 | 0.95 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL3689188 | 0.84 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6262063 | 0.84 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL3684231 | 0.83 | ITGAV (0.56) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL3692823 | 0.83 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| Hydrochloric Acid SCHEMBL29416400 | 0.82 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5 | |
| Hydrochloric Acid SCHEMBL6424214 | 0.82 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL3694317 | 0.82 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL3686967 | 0.81 | ITGAV (0.56) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL3686215 | 0.81 | ITGB3 (0.76) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |