Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877964 | 1.00 | EGFR (0.57) | EGFR | |
| SCHEMBL29257946 | 0.87 | EGFR (0.47) | EGFR | |
| SCHEMBL30701583 | 0.86 | BRD4 (0.44) | EGFR | |
| SCHEMBL25227377 | 0.84 | EGFR (0.81) | EGFR | |
| SCHEMBL30459687 | 0.84 | EGFR (0.81) | EGFR | |
| SCHEMBL26906791 | 0.81 | EGFR (0.84) | EGFR | |
| SCHEMBL22025654 | 0.80 | EGFR (0.86) | EGFR | |
| SCHEMBL29877050 | 0.80 | EGFR (0.64) | EGFR | |
| SCHEMBL25001408 | 0.80 | EGFR (0.64) | EGFR | |
| Hydrochloric Acid SCHEMBL29877259 | 0.79 | EGFR (0.64) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888108-B | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116888108-A | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2023-10-13 | — | — | CN | disclosed |