Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 18/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877964 | 0.86 | EGFR (0.57) | EGFR | |
| SCHEMBL29257889 | 0.86 | EGFR (0.57) | EGFR | |
| SCHEMBL29188529 | 0.83 | EGFR (0.62) | ALKEGFR | |
| SCHEMBL26906586 | 0.80 | EGFR (0.66) | EGFR | |
| SCHEMBL26906805 | 0.79 | EGFR (0.68) | EGFR | |
| SCHEMBL25002403 | 0.79 | EGFR (0.50) | EGFR | |
| SCHEMBL29877082 | 0.79 | EGFR (0.50) | EGFR | |
| Hydrochloric Acid SCHEMBL29257920 | 0.78 | EGFR (0.49) | EGFR | |
| SCHEMBL29877244 | 0.77 | BRD4 (0.56) | BRD4ALKEGFR | |
| SCHEMBL25001663 | 0.77 | EGFR (0.47) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888108-B | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116888108-A | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2023-10-13 | — | — | CN | disclosed |