Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.79 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258176 | 0.88 | NAMPT (0.62) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL20379207 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29258331 | 0.88 | NAMPT (0.68) | NAMPTALDH1A1MAPT | |
| SCHEMBL29258280 | 0.88 | NAMPT (0.80) | NAMPTALDH1A1MAPT | |
| SCHEMBL29258556 | 0.88 | NAMPT (0.61) | NAMPTCA9CA1CA2LSS | |
| SCHEMBL29258470 | 0.88 | NAMPT (0.64) | NAMPTCA9ALDH1A1MAPT | |
| SCHEMBL29258259 | 0.88 | NAMPT (0.79) | NAMPTCA9CA1CA2LSS | |
| SCHEMBL29258204 | 0.87 | NAMPT (0.80) | NAMPTCA9CA1CA2LSS | |
| SCHEMBL29258574 | 0.85 | NAMPT (0.80) | NAMPTALDH1A1 | |
| SCHEMBL29258262 | 0.85 | NAMPT (0.78) | NAMPTCA9CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |