Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258111 | 0.88 | NAMPT (0.79) | NAMPTALDH1A1MAPTCA9CA1 | |
| SCHEMBL29258555 | 0.88 | NAMPT (0.79) | NAMPT | |
| SCHEMBL29258244 | 0.88 | NAMPT (0.60) | NAMPTALDH1A1MAPTCA9SMN1; SMN2 | |
| SCHEMBL29258798 | 0.87 | NAMPT (0.58) | NAMPTALDH1A1MAPTCA9SMN1; SMN2 | |
| SCHEMBL29258262 | 0.86 | NAMPT (0.78) | NAMPTALDH1A1MAPTCA9CA1 | |
| SCHEMBL29258807 | 0.85 | NAMPT (0.80) | NAMPT | |
| SCHEMBL29258207 | 0.84 | NAMPT (0.62) | NAMPT | |
| SCHEMBL29258082 | 0.84 | NAMPT (0.65) | NAMPTALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29258126 | 0.82 | NAMPT (0.67) | NAMPTALDH1A1MAPTCA9SMN1; SMN2 | |
| SCHEMBL29258304 | 0.81 | NAMPT (0.78) | NAMPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |