SCHEMBL29258151

SCHEMBL29258151

O=C(NCc1ccncc1)Nc1ccc(C(=O)NCc2ccccc2OC(F)(F)F)cc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379612 0.87 NAMPT (1.00) NAMPT
SCHEMBL20379328 0.87 NAMPT (0.76) NAMPT
SCHEMBL29258090 0.85 NAMPT (0.75) NAMPT
SCHEMBL20388950 0.84 NAMPT (0.63) NAMPT
SCHEMBL29258634 0.84 NAMPT (0.89) NAMPT
SCHEMBL20379924 0.83 NAMPT (0.78) NAMPT
SCHEMBL20379294 0.83 NAMPT (1.00) NAMPT
SCHEMBL29258157 0.82 NAMPT (0.77) NAMPT
SCHEMBL29258279 0.82 NAMPT (0.82) NAMPT
SCHEMBL20379654 0.82 NAMPT (0.78) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN claimed
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN disclosed