SCHEMBL29258157

SCHEMBL29258157

O=C(NCc1ccncc1)Nc1ccc(NS(=O)(=O)Cc2ccccc2OC(F)(F)F)cc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29881511 0.87 NAMPT (1.00) NAMPT
SCHEMBL20379655 0.87 NAMPT (1.00) NAMPT
SCHEMBL20379280 0.86 NAMPT (0.76) NAMPT
SCHEMBL29881759 0.86 NAMPT (0.76) NAMPT
SCHEMBL29258110 0.85 NAMPT (0.71) NAMPT
SCHEMBL20379924 0.84 NAMPT (0.78) NAMPT
SCHEMBL29258137 0.83 NAMPT (0.74) NAMPT
SCHEMBL29258151 0.82 NAMPT (0.77) NAMPT
SCHEMBL29258377 0.82 NAMPT (0.73) NAMPT
SCHEMBL20379342 0.82 NAMPT (0.73) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN claimed
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN disclosed