Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258235 | 0.91 | NAMPT (0.55) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258315 | 0.90 | NAMPT (0.57) | NAMPTMEN1KMT2AMMP1MMP2 | |
| SCHEMBL29258519 | 0.89 | NAMPT (0.67) | NAMPTMEN1KMT2A | |
| SCHEMBL29258153 | 0.89 | MEN1 (0.62) | NAMPTMEN1KMT2A | |
| SCHEMBL29258274 | 0.89 | NAMPT (0.67) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL30927210 | 0.89 | CA12 (0.53) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258399 | 0.89 | CA12 (0.53) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL30927236 | 0.88 | NAMPT (0.68) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258225 | 0.88 | NAMPT (0.68) | NAMPTCA12CA1CA2CA9 | |
| SCHEMBL29258650 | 0.88 | NAMPT (0.58) | NAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |