Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258197 | 0.91 | KMT2A (0.56) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258315 | 0.90 | NAMPT (0.57) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258519 | 0.89 | NAMPT (0.67) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258153 | 0.89 | MEN1 (0.62) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258173 | 0.89 | NAMPT (0.67) | NAMPTMEN1KMT2ACA12CA1 | |
| SCHEMBL30927198 | 0.89 | NAMPT (0.55) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258516 | 0.89 | NAMPT (0.55) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL30927229 | 0.88 | NAMPT (0.68) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258194 | 0.88 | NAMPT (0.68) | NAMPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL29258650 | 0.88 | NAMPT (0.58) | NAMPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |