Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 10/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258194 | 0.91 | NAMPT (0.68) | KMT2AMEN1KDM4EHTTNAMPT | |
| SCHEMBL30927229 | 0.91 | NAMPT (0.68) | KMT2AMEN1KDM4EHTTNAMPT | |
| SCHEMBL29258274 | 0.91 | NAMPT (0.67) | KMT2AMEN1KDM4EHTTCA12 | |
| SCHEMBL29258361 | 0.90 | MEN1 (0.56) | KMT2AMEN1KDM4EHTTCA12 | |
| SCHEMBL30927198 | 0.88 | NAMPT (0.55) | KMT2AMEN1KDM4EHTTNAMPT | |
| SCHEMBL29258516 | 0.88 | NAMPT (0.55) | KMT2AMEN1KDM4EHTTNAMPT | |
| SCHEMBL29258235 | 0.88 | NAMPT (0.55) | KMT2AMEN1KDM4EHTTCA12 | |
| SCHEMBL30927210 | 0.86 | CA12 (0.53) | KMT2AMEN1KDM4EHTTCA12 | |
| SCHEMBL29258399 | 0.86 | CA12 (0.53) | KMT2AMEN1KDM4EHTTCA12 | |
| SCHEMBL29258315 | 0.85 | NAMPT (0.57) | KMT2AMEN1KDM4EHTTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |