Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.82 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258772 | 0.91 | NAMPT (0.80) | NAMPTPLA2G1BMAPTSMN1; SMN2ATG4B | |
| SCHEMBL20379415 | 0.90 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29258160 | 0.88 | NAMPT (0.81) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258778 | 0.86 | NAMPT (0.81) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258807 | 0.85 | NAMPT (0.80) | NAMPT | |
| SCHEMBL29258636 | 0.83 | NAMPT (0.80) | NAMPTSMN1; SMN2 | |
| SCHEMBL29258655 | 0.83 | NAMPT (0.80) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258122 | 0.83 | NAMPT (0.62) | NAMPT | |
| SCHEMBL29258230 | 0.83 | NAMPT (0.62) | NAMPTPLA2G1BMAPTSMN1; SMN2ATG4B | |
| SCHEMBL29258214 | 0.81 | NAMPT (0.78) | NAMPTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |