Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.80 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258200 | 0.91 | NAMPT (0.82) | NAMPTPLA2G1BMAPTSMN1; SMN2ATG4B | |
| SCHEMBL20379351 | 0.89 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29258214 | 0.89 | NAMPT (0.78) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258267 | 0.88 | NAMPT (0.79) | NAMPT | |
| SCHEMBL29258262 | 0.86 | NAMPT (0.78) | NAMPTMAPT | |
| SCHEMBL29258230 | 0.85 | NAMPT (0.62) | NAMPTPLA2G1BMAPTSMN1; SMN2ATG4B | |
| SCHEMBL29258126 | 0.85 | NAMPT (0.67) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258304 | 0.84 | NAMPT (0.78) | NAMPTSMN1; SMN2 | |
| SCHEMBL29258266 | 0.84 | NAMPT (0.65) | NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL29258231 | 0.84 | NAMPT (0.78) | NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |