Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258160 | 0.89 | NAMPT (0.81) | NAMPTALDH1A1 | |
| SCHEMBL20380063 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29258304 | 0.88 | NAMPT (0.78) | NAMPT | |
| SCHEMBL29258772 | 0.88 | NAMPT (0.80) | NAMPT | |
| SCHEMBL29258126 | 0.87 | NAMPT (0.67) | NAMPTALDH1A1 | |
| SCHEMBL29258266 | 0.86 | NAMPT (0.65) | NAMPTALDH1A1 | |
| SCHEMBL29258231 | 0.86 | NAMPT (0.78) | NAMPTALDH1A1 | |
| SCHEMBL29258262 | 0.86 | NAMPT (0.78) | NAMPTALDH1A1 | |
| SCHEMBL29258214 | 0.84 | NAMPT (0.78) | NAMPTALDH1A1 | |
| SCHEMBL29258574 | 0.84 | NAMPT (0.80) | NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |