Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 12/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927215 | 1.00 | MEN1 (0.56) | MEN1KMT2AKDM4ENAMPTHDAC3 | |
| SCHEMBL29258361 | 0.91 | MEN1 (0.56) | MEN1KMT2AKDM4ENAMPTHDAC3 | |
| SCHEMBL29258100 | 0.89 | NAMPT (0.69) | MEN1KMT2ANAMPTMAPT | |
| SCHEMBL30927201 | 0.89 | NAMPT (0.69) | MEN1KMT2ANAMPTMAPT | |
| SCHEMBL29258194 | 0.88 | NAMPT (0.68) | MEN1KMT2AKDM4ENAMPTMAPT | |
| SCHEMBL30927229 | 0.88 | NAMPT (0.68) | MEN1KMT2AKDM4ENAMPTMAPT | |
| SCHEMBL29258225 | 0.88 | NAMPT (0.68) | MEN1KMT2ANAMPTMAPT | |
| SCHEMBL30927236 | 0.88 | NAMPT (0.68) | MEN1KMT2ANAMPTMAPT | |
| SCHEMBL29258153 | 0.88 | MEN1 (0.62) | MEN1KMT2AKDM4ENAMPTMAPT | |
| SCHEMBL30927200 | 0.87 | NAMPT (0.53) | MEN1KMT2AKDM4ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |