Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258556 | 0.88 | NAMPT (0.61) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL29258140 | 0.88 | NAMPT (0.77) | NAMPT | |
| SCHEMBL29258244 | 0.88 | NAMPT (0.60) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL29258176 | 0.87 | NAMPT (0.62) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL29258266 | 0.86 | NAMPT (0.65) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL29258122 | 0.85 | NAMPT (0.62) | NAMPTCA9CA1CA2LSS | |
| SCHEMBL29258168 | 0.84 | NAMPT (0.64) | NAMPTCA9CA1CA2 | |
| SCHEMBL29258651 | 0.84 | NAMPT (0.63) | NAMPTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29258126 | 0.82 | NAMPT (0.67) | NAMPTCA9CA1CA2ALDH1A1 | |
| SCHEMBL29258262 | 0.81 | NAMPT (0.78) | NAMPTCA9CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | claimed |
| CN-118108664-A | NAMPT agonist and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-05-31 | — | — | CN | disclosed |