SCHEMBL2925902

SCHEMBL2925902

Cc1c(CC(=O)O)c2cccnc2n1CCCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925018 0.94 PTGDR2 (0.78) PTGDR2
SCHEMBL1939991 0.86 PTGDR2 (1.00) PTGDR2
SCHEMBL2920409 0.83 PTGDR2 (0.61) PTGDR2
SCHEMBL2923946 0.82 PTGDR2 (0.67) PTGDR2
SCHEMBL1940594 0.80 PTGDR2 (1.00) PTGDR2
SCHEMBL1941332 0.80 PTGDR2 (1.00) PTGDR2
SCHEMBL1940106 0.80 PTGDR2 (1.00) PTGDR2
SCHEMBL1939826 0.80 PTGDR2 (1.00) PTGDR2
SCHEMBL1939892 0.79 PTGDR2 (0.80) PTGDR2
SCHEMBL1939990 0.79 PTGDR2 (0.79) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960398-B1 ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY NOVARTIS AG (CH) 2010-09-29 EP disclosed
EP-2225223-A2 ORGANIC COMPOUNDS Boehringer Ingelheim International GmbH (DE) 2010-09-08 EP disclosed
WO-2009065919-A2 NOVEL COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-05-28 WO disclosed
US-20080312229-A1 Organic Compounds NOVARTIS AG 2008-12-18 US disclosed
EP-1960398-A1 ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY Novartis AG (CH) 2008-08-27 EP disclosed
WO-2007065683-A1 ARYL ACETIC ACID AND ESTER DERIVATIVES AND THEIR USES AS ANTIINFLAMMATORY NOVARTIS AG (CH) 2007-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312229-A1 Organic Compounds DRD4, DRD1, SLC10A6 PTGDR2 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.