Naphthoquinone

Naphthoquinone

SCHEMBL29259751

Cc1ncc[nH]1.O=C1C=CC(=O)c2ccccc21

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
IDO1 P14902 4/20 0.50
CDC25B P30305 3/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
SNCA P37840 2/20 0.50
AKT1 P31749 1/20 0.50
MAP2K1 Q02750 1/20 0.50
PIN1 Q13526 1/20 0.50
EHMT2 Q96KQ7 1/20 0.50
NSD1 Q96L73 1/20 0.50
EHMT1 Q9H9B1 1/20 0.50
S100A4 P26447 2/20 0.47
TP53 P04637 2/20 0.39
TSHR P16473 1/20 0.39
CSNK1A1 P48729 1/20 0.38
TYRO3 Q06418 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
TLK2 Q86UE8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL27339477 0.82 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2IDO1TP53TSHR
Benzene SCHEMBL28115465 0.76 ALDH1A1 (0.89) ALDH1A1SMN1; SMN2TAAR1NISCHMEN1
Benzene SCHEMBL1648398 0.76 ALDH1A1 (0.89) ALDH1A1SMN1; SMN2TAAR1NISCHMEN1
SCHEMBL167 0.76
SCHEMBL9244226 0.76 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TAAR1NISCHMEN1
SCHEMBL9145211 0.76 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TAAR1NISCHMEN1
Toluene SCHEMBL27273046 0.75 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2MAP2K1TP53TSHR
Formaldehyde SCHEMBL28146054 0.74
Bromide SCHEMBL5133664 0.73
Hydrochloric Acid SCHEMBL19552313 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768801-A Condensed quinone oxime imidazoles and their onium derivatives, their preparation and use 上海交通大学 2023-09-19 CN disclosed