Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | WIZ | O95785 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260050 | 0.95 | CRBN (0.50) | CRBNESR1IKZF2CSNK1A1WIZ | |
| SCHEMBL29260052 | 0.95 | CRBN (0.50) | CRBNESR1IKZF2CSNK1A1WIZ | |
| SCHEMBL31586284 | 0.87 | CRBN (0.58) | CRBNESR1IKZF2CSNK1A1WIZ | |
| SCHEMBL30938263 | 0.86 | CRBN (0.62) | CRBNCHRM2DDB1IKZF3 | |
| SCHEMBL26814219 | 0.86 | CRBN (0.62) | CRBNCHRM2DDB1IKZF3 | |
| SCHEMBL20231556 | 0.85 | CRBN (0.67) | CRBNESR1IKZF2CSNK1A1WIZ | |
| SCHEMBL30135945 | 0.84 | ESR1 (0.45) | CRBNESR1IKZF2CSNK1A1WIZ | |
| SCHEMBL20231971 | 0.84 | CRBN (0.61) | CRBNESR1IKZF2WIZIKZF1 | |
| Hydrochloric Acid SCHEMBL31205477 | 0.84 | CRBN (0.65) | CRBNESR1IKZF2CSNK1A1WIZ | |
| Hydrochloric Acid SCHEMBL31205353 | 0.84 | CRBN (0.65) | CRBNESR1IKZF2CSNK1A1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |