Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 19/20 | 0.66 |
| ▸ | MMP2 | P08253 | 4/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745396 | 0.94 | ADAMTS5 (0.72) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL23745413 | 0.92 | ADAMTS5 (0.69) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL31121194 | 0.92 | ADAMTS5 (0.69) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL29835185 | 0.85 | ADAMTS5 (0.54) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL29250233 | 0.85 | ADAMTS5 (0.54) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL23745405 | 0.85 | ADAMTS5 (0.54) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL29835157 | 0.85 | ADAMTS5 (0.54) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL23745281 | 0.85 | ADAMTS5 (0.62) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL23745361 | 0.83 | ADAMTS5 (0.69) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 | |
| SCHEMBL23745296 | 0.83 | ADAMTS5 (0.68) | ADAMTS5MMP2MMP13ADAMTS4ADAMTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754635-B | Condensed ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-113754635-A | Fused ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2021-12-07 | — | — | CN | disclosed |