Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930931 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL2926285 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL2926278 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL2932804 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL2930929 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL2932805 | 1.00 | BACE1 (0.37) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL3773623 | 0.92 | L3MBTL1 (0.36) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL3773618 | 0.92 | L3MBTL1 (0.36) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL3773622 | 0.92 | L3MBTL1 (0.36) | BACE1BACE2L3MBTL1MAPTKMT2A | |
| SCHEMBL3774085 | 0.88 | BACE1 (0.47) | BACE1BACE2L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233474-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-09-29 | — | — | EP | disclosed |